2 Million Dogs – The Blog

Cancer. Touches. Everyone.

Posts Tagged ‘comparative oncology’

Breast Cancer And Dogs: The Next ‘Canaries In The Coal Mine’?

Posted by Erich Trapp on October 12, 2013

By Lynne Peeples, Huffington Post

(Thanks to Lynne Peeples and the Huffington Post for this article.)

When his beloved Great Pyrenees Malcolm died of bone cancer at age 6, Luke Robinson resolved to learn why.

“I didn’t even know dogs could get cancer,” he said.

The nagging mystery would send Robinson walking over 2,000 miles from Austin, Texas, to Boston with his other two dogs to raise awareness for canine cancer. It would also inspire his launch of an organization devoted to finding an answer — through the discovery of links between dog and human tumors.

“Breast cancer was the first cancer we funded,” said Robinson, co-founder of the nonprofit 2 Million Dogs . “Under a microscope, a mammary tumor from a dog and from a person look the same.”

As the prolific pink ribbons seek to remind us this month, breast cancer’s grip remains strong and its reach ever-expanding. One in eight women in the U.S. will now face the diagnosis — a rise of 40 percent in just one generation.

Perhaps less well-known, however, is that most breast cancers are not hereditary and that cancer is the leading disease-related killer of dogs, with mammary tumors the most common type afflicting females. (Early spaying significantly reduces the risk of such tumors.) These facts, combined with mounting evidence of harm posed by certain chemicals used on carpets, couches, food bowls, squeaky toys and manicured lawns enjoyed by people and pets — has led some experts and advocates to recommend a shift in breast cancer research and funding.

Only about 10 percent of breast cancer research dollars are devoted to its environmental causes, according to a federal interagency report published in February.

Luke Robinson and his two dogs, Murphy and Hudson, peer from a tent during his canine cancer awareness walk from Austin, Tex. to Boston in 2008. (Marei Burnfield)

Luke Robinson and his two dogs, Murphy and Hudson, peer from a tent during his canine cancer awareness walk from Austin, Tex. to Boston in 2008. (Marei Burnfield)

“Dogs drink our same water, they are exposed to the same toxins,” Robinson said. “The logical assumption is that indeed there is an environmental basis for these cancers. But a lot of research and funding comes from pharmaceutical companies. And there’s no money in cause and prevention.”

Overall, growing interest in canine cancer has led to new comparative oncology research at the University of Pennsylvania and Princeton University, with financial help from 2 Million Dogs. Investigators are treating shelter dogs that have developed mammary cancer, while gleaning information about the progression of the disease. The researchers hope to identify treatments that will benefit both dogs and humans.

Penn veterinarians previously studied dogs involved in September 11 search and rescue missions thought to be exposed to chemicals in the rubble. They found no elevated rates of major health problems in the decade after the attack.

To read the entire article by Huffington Post, please follow this link.

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Non-Resectable

Posted by Erich Trapp on September 22, 2013

Photo from left to right:  Drs. Richard Goldstein and Allyson Berent; Luke Robinson, Founder of 2 Million Dogs; Chick Weisse; Kate Coyne (CEO of AMC); Ginger Morgan, Executive Director of 2 Million Dogs; Nicole Leibman and Ann Hohenhaus.

From left to right: Drs. Richard Goldstein and Allyson Berent; Luke Robinson, Founder of 2 Million Dogs; Dr. Chick Weisse; Kate Coyne (CEO of AMC); Ginger Morgan, Executive Director of 2 Million Dogs; Drs. Nicole Leibman and Ann Hohenhaus. Indiana and Hudson.

 

Sunday, September 22, 2013

(by Luke Robinson)

“I’m sorry.  It’s inoperable.”

How many of you have heard these words? That diagnosis from Steve Withrow about Murphy’s nasal tumor still haunts my thoughts some two years post mortem.

2 Million Dogs is funding a two year, $80,000 drug delivery study with Animal Medical Center in Manhattan and Sloan Kettering.

The first phase of the study is urogenital cancer in dogs since, at the point of diagnosis, the prognosis is pretty grim.  Less than 30% of bladder cancer patients respond to traditional treatment and since surgical intervention isn’t a viable option, the need for target therapeutics is essential.

We all know that dosing chemo in dogs is drastically less than that in humans and if we can get the right drug directly into the tumor, we may achieve therapeutic drug levels at 40X the current regimen.  There are other potential benefits such as cost savings, but they are ancillary to our aims.

Speaking of… here’s my press release statement:

“It is an honor to work with two prestigious institutions in the fields of veterinarian medicine and cancer research.  2 Million Dogs’ scientific objectives in funding cancer studies are collaborative and comparative in both spirit and scope and this study is a shining example of that.  Cancer touches us all.  It is a cross species disease and now more than ever it is imperative for us work together to end this epidemic.”

More importantly, I’ve come to know the principal investigator, Chick, on a more personal level and I feel he has the vision, fortitude, and fire to make significant strides in the field of comparative oncology.

 

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13 – 13 – 13

Posted by Erich Trapp on September 4, 2013

(by Ginger Morgan, Executive Director, 2 Million Dogs)

As I write this, summer is coming to a close. I’m fortunate that so far, 2013 has kept me busy working for you and this cause in the best of ways.

Faye Morgan.

Faye Morgan.

In August, we posted stories of dogs who’d had cancer to our Facebook page, and you responded with words of comfort, shares, and votes in our calendar contest. Thank you. The 2 Million Dogs family continues to impress me with their dedication every day.

I lost another dog to cancer this summer — my beloved Faye (pictured). Like many of you, I let these experiences fuel my fire for this cause. I’m writing this to acknowledge that you are our best resource — your input, your stories, your comments, and your support. With that in mind, I’m pleased to announce that moving forward, I will personally update you on 2 Million Dogs, here on our blog in the coming months. I’ll share helpful tips and information about canine cancer, announce special events where you can participate or meet up with other supporters in our community, or update you on the latest and greatest with the cause.

As we support comparative oncology research, the leadership at 2 Million Dogs steadily seeks new ways to help you to spread the word about its importance and our mutual belief that a cure for cancer is out there. We get many comments that some of you want to participate in a walk but cannot, mainly due to prior commitments or bum knees.

Our next event is just for you. And everyone, actually.

It’s called 13-13-13.

 
On September 13:

* Ask 13 friends on Facebook to “Like” the 2 Million Dogs Facebook page here.

* Donate $13 to canine cancer research at here.    Please click on the orange donate button.

* Write 13-13-13 on a piece of paper, hold it up, take a selfie (a photo of yourself), and post your picture to Facebook, Twitter, or Instagram with the hashtag #2milliondogs.

I hope you all participate in our 13-13-13 event, and get a chance to join us at one of our many Puppy Up! Walks this Fall.

 

Get involved -- Pete and Ginger

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2014 Calendar Contest Results

Posted by Erich Trapp on August 9, 2013

"That was FUN. Let's do it again!"

“That was FUN. Let’s do it again!”

Congratulations to the Winners and ALL of the Contestants in the 2014 Cancer Can’t Keep a Good Dog Down Calendar Contest!

Here’s the final count. Any votes that came in after the midnight EDT deadline did not apply.

Our top 13 winners are:

1 Trooper Collins 2140
2 Czar Viney 1460
3 Beta Yadao 1270
4 Gracie Calvo 1120
5 Blondie Henley 1000
6 Bentley Linaberry 1000
7 Molly Su Applegate 1000
8 Sheba Marie Pyle 960
9 Gracie Martin 940
10 Yukon Harris 900
11 Calamity Jane Rockwell 865
12 Kailech Cummins 785
13 Jigsaw Allgood 730

 

Also appearing in the Gallery Section will be:

Sunny Osborne 720
Pugsley Granberry 700
Maggie Snow-Cormier 660
Murphy Morris 640
Kyle Golz 510
Roscoe Behrle 510
Annie Graffunder 420
Eva Dupre 375
Shadow Wade 272
Merlin Miltner 225
Leela Decker 220
Guinnes Litt 185
Nestle Epstein 185
Joey Hanson 160
Jake Turner 155
Mogli DeWald 120
Murphy Hansen 120
Chance Galante 105
Mauser Lopez 102
Savannah Wolff 100
Marshal Fortson 85
Sundae Reed 80
Jackie Pilarski 70
Jake Pilarski 70
Remedy Pilarski 70
Abby Lavin 60
Charlie Mortensen 50
Ginger Suh Quimby 50
Angel Warner 30
Desi Scroggins 30
Harley Waterloo 30
Jessica Baud 30
Merlin Kisiel 30
Riley Robinson 30
Buckeye Belle Eaton 25
Ruby Warner 25
Saffron Brandstetter 25
Zoe Brandstetter 25
Harley Giazzon 20
Maggie Smith 20
Mischa Brown 20
Angel Cavella 15
Angel Treglia 15
Crystal No Last Name 15
Little Bear Hain 15
Max Waterloo 15
Chloe Bear Forster 10
Lexi Sutphen 10
Rinti du Plessis 10
Uma Neet-Whitaker 10
Bailey Sandberg 5
Bebe Moroz 5
Ingrid Neet-Whitaker 5
Kanye Parry 5

 

Because of your generous donations, we will be able to fund another research study with The Broad Institute this year. Our top 13 winners will determine which study we fund, and we’ll announce that soon here on our blog and our website, so please bookmark both.

Thank you for being a part of the 2 Million Dogs’ community.

Puppy Up!

 

Posted in 2014 Calendar Contest, Fundraiser, Research, Stories | Tagged: , , , , , , | 2 Comments »

This Morning’s Calendar Totals – August 7, 2013

Posted by Erich Trapp on August 7, 2013

It would certainly help with voting if I had thumbs!

It would certainly help with voting if I had thumbs!

These totals were recorded at 7:30 CDT this morning. Voting ends August 8 at 12 midnight Eastern time, so please don’t wait until the last minute to vote.

 

VOTE for your favorite puppers HERE.

 

Thanks to everyone for your patience yesterday when the voting site was down for a couple of hours. Let’s hope they have resolved their issues.

 

Czar Viney 1385
Yukon Harris 770
Trooper Collins 725
Molly Su Applegate 605
Kailech Cummins 500
Bentley Linaberry 470
Blondie Henley 470
Calamity Jane Rockwell 470
Maggie Snow-Cormier 460
Kyle Golz 410
Gracie Martin 400
Pugsley Granberry 365
Gracie Calvo 315
Beta Yadao 300
Eva Dupre 295
Shadow Wade 267
Jigsaw Allgood 255
Roscoe Behrle 255
Murphy Morris 245
Sunny Osborne 235
Merlin Miltner 225
Leela Decker 190
Sheba Marie Pyle 190
Guinnes Litt 185
Nestle Epstein 185
Annie Graffunder 170
Jake Turner 145
Joey Hanson 135
Mogli DeWald 120
Chance Galante 105
Savannah Wolff 100
Sundae Reed 80
Jackie Pilarski 70
Jake Pilarski 70
Remedy Pilarski 70
Mauser Lopez 67
Murphy Hansen 65
Abby Lavin 60
Charlie Mortensen 50
Ginger Suh Quimby 50
Desi Scroggins 30
Harley Waterloo 30
Jessica Baud 30
Merlin Kisiel 30
Riley Robinson 30
Buckeye Belle Eaton 25
Saffron Brandstetter 25
Zoe Brandstetter 25
Harley Giazzon 20
Maggie Smith 20
Marshal Fortson 20
Mischa Brown 20
Angel Cavella 15
Angel Treglia 15
Crystal No Last Name 15
Ruby Warner 15
Angel Warner 10
Chloe Bear Forster 10
Lexi Sutphen 10
Rinti du Plessis 10
Uma Neet-Whitaker 10
Bailey Sandberg 5
Bebe Moroz 5
Ingrid Neet-Whitaker 5
Kanye Parry 5
Little Bear Hain 5
Max Waterloo 5

 

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2014 Calendar Totals Saturday, August 3, 2013 8:30 AM CDT

Posted by Erich Trapp on August 3, 2013

"Soon I'll be sniffin' out the winners ..."

“Soon I’ll be sniffin’ out the winners …”

Here are the 2014 Cancer Can’t Keep a Good Dog Down calendar contest totals as of 8:30 AM CDT, Saturday August 3.

You have until August 8 at midnight EDT to cast your votes for your favorite puppers. There are a number of new frontrunners, so keep track of your favorite pups to keep them in the running.

LOOK! Everyone now has votes, thanks to our generous donors.

We’ll be posting again in a couple of days. Stay tuned and good luck!

Czar Viney 1305
Trooper Collins 725
Yukon Harris 510
Kailech Cummins 500
Calamity Jane Rockwell 470
Molly Su Applegate 455
Kyle Golz 310
Beta Yadao 300
Gracie Martin 300
Pugsley Granberry 290
Maggie Snow-Cormier 285
Gracie Calvo 265
Eva Dupre 265
Roscoe Behrle 240
Jigsaw Allgood 240
Murphy Morris 220
Sunny Osborne 215
Merlin Miltner 205
Blondie Henley 195
Guinnes Litt 185
Nestle Epstein 185
Shadow Wade 182
Bentley Linaberry 180
Sheba Marie Pyle 180
Leela Decker 150
Annie Graffunder 145
Jake Turner 140
Mogli DeWald 80
Jackie Pilarski 70
Jake Pilarski 70
Remedy Pilarski 70
Mauser Lopez 67
Abby Lavin 60
Savannah Wolff 55
Chance Galante 55
Charlie Mortensen 50
Ginger Suh Quimby 50
Murphy Hansen 50
Sundae Reed 50
Jessica Baud 30
Desi Scroggins 30
Merlin Kisiel 30
Harley Waterloo 30
Riley Robinson 30
Buckeye Belle Eaton 25
Saffron Brandstetter 25
Zoe Brandstetter 25
Marshal Fortson 20
Maggie Smith 20
Angel Treglia 15
Crystal No Last Name 15
Angel Cavella 15
Harley Giazzon 15
Mischa Brown 15
Lexi Sutphen 10
Rinti du Plessis 10
Uma Neet-Whitaker 10
Ingrid Neet-Whitaker 5
Max Waterloo 5
Angel Warner 5
Bailey Sandberg 5
Bebe Moroz 5
Chloe Bear Forster 5
Kanye Parry 5
Ruby Warner 5

 

 

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The Totals, They Are A Changin’.

Posted by Erich Trapp on July 29, 2013

Every toe counts when you're doing addition.

Every toe counts when you’re doing addition.

2014 Calendar Totals as of July 29 2013 8:30 AM CDT

We’ve had a few new comers to the top 13 contestants. And lots of dogs are neck-and-neck or tied. Keep track of your favorite dogs because things change pretty fast as we get closer to the end of voting. Remember, you have until August 8th at midnight EDT to get your pupper in the running or keep him or her there. And it’s always the last few days of the contest when the competition gets heated and things get really interesting.

Vote HERE.

Need a few ideas to help get more votes? Check out our last blog for some great tips.

We’ll keep counting if you’ll keep voting!

Czar Viney       1270

Trooper Collins       725

Kailech Cummins       470

Molly Su Applegate       430

Yukon Harris       385

Calamity Jane Rockwell       370

Kyle Golz       310

Beta Yadao       300

Gracie Martin       295

Pugsley Granberry       290

Gracie Calvo       265

Maggie Snow-Cormier       260

Merlin Miltner       205

Murphy Morris       195

Guinnes Litt       185

Roscoe Behrle       175

Bentley Linaberry       165

Annie Graffunder       145

Blondie Henley       145

Nestle Epstein       140

Shadow Wade       137

Jigsaw Allgood       115

Eva Dupre        110

Mogli DeWald       80

Jackie Pilarski       70

Jake Pilarski       70

Mauser Lopez       67

Abby Lavin       55

Sunny Osborne       55

Charlie Mortensen       50

Ginger Suh Quimby       50

Remedy Pilarski        50

Leela Decker       50

Murphy Hansen        45

Savannah Wolff             45

Sheba Marie Pyle       45

Sundae Reed       45

Jessica Baud       30

Desi Scroggins       30

Merlin Kisiel       30

Buckeye Belle Eaton       25

Harley Waterloo       25

Saffron Brandstetter       25

Zoe Brandstetter       25

Marshal Fortson       20

Jake Turner       20

Maggie Smith       20

Angel Treglia       15

Crystal No Last Name        15

Lexi Sutphen       10

Riley Robinson       10

Rinti du Plessis       10

Uma Neet-Whitaker       10

Ingrid Neet-Whitaker       5

Max Waterloo       5

Angel Cavella       5

Angel Warner       5

Bailey Sandberg            5

Bebe Moroz       5

Chance Galante       5

Chloe Bear Forster       5

Harley Giazzon       5

Kanye Parry       5

Ruby Warner       5

Mischa Brown       0

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Eight Ways to Get More Votes in our “Cancer Can’t Keep a Good Dog Down” Calendar Contest

Posted by Erich Trapp on July 25, 2013

boy-abacus_~k3972678

“Now, let’s see. Charlie is dark green, Blondie is yellow, Desi is purple, Sundae is turquoise … no wait — Nestle is purple and Saffron is yellow… no, that’s not right either. Oh bother! There has to be an easier way to count these votes.”

(by Teri Mo)

Twice now, 2 Million Dogs has posted the running totals in our “Cancer Can’t Keep a Good Dog Down” Calendar Contest.

If you haven’t heard of the contest, it’s Luke Robinson’s fun little brainchild. Once a year, we ask people whose dogs currently have cancer or dog owners who have lost a dog to cancer to send us their dogs’ stories and photos.

We compile the stories and let the public decide which pups will be in next year’s 2 Million Dogs’ calendar. The public votes HERE, and the proceeds support comparative oncology (cancer) research.

It’s still early in the contest, and a few of our pups — our sweet, big-eyed, adorable pups — have no votes yet. (Cue crowd going “Awwwwwww.”)

But don’t worry — there’s plenty of time to get votes! Here’s how to boost those numbers:

  • When we feature your favorite dog on our 2 Million Dogs’ Facebook page, share it on your Facebook, Twitter, and Pinterest accounts, and use the words “vote and share!” Nothing helps you make your case like big, irresistible puppy-dog eyes.
  • Host a Puppy Up! Blitz on your lunch hour and invite your co-workers. Pick a dog for each co-worker. Whoever raises the most money for their dog by the end of the lunch break gets a box of fresh doughnuts the next morning.
  • Ask your co-workers to participate in a Give Up Your Daily Drink (soda or coffee) For Cancer Day. Everyone gives up his or her daily latte or soda, and the right to complain about it is “bought” by voting for your favorite pup with the money you didn’t spend on an Iced Calorie Bomb with three pumps of vanilla.
  • Not a social media person? E-mail friends and family asking each for $10.00 worth of votes for your pup. Avoid caps lock (SHOUTING), and keep the body of your e-mail short and sweet. (Feel free to use anything we’ve written here when explaining the contest.)
  • Write a silly or sweet song about your experience with your dog’s cancer, and post it on YouTube with the link to your dog’s calendar contest fundraising page. This is guaranteed to boost those numbers.
  • If your dog isn’t a contestant, pick your favorite underdog and dare all your friends to do their good deed for the day by bombarding that page with votes.
  • Tell your family and friends that the votes are a birthday gift to you. Tell them the only thing you want for your birthday is votes for your pup.
  • If your neighbors have dogs or they just miss your pup, get their e-mail addresses and share the contest with them.

This is all going to a good cause, so everyone wins. Save the puppies, save the people! Puppy up!

(Teri Mo is our resident social media guru.)

Posted in 2014 Calendar Contest, Fundraiser, Research, Stories | Tagged: , , , , , , , , | 1 Comment »

More Ways to Help

Posted by Erich Trapp on July 23, 2013

broad boxerOur “Cancer Can’t Keep a Good Dog Down” 2014 calendar is in full swing, so stop by and vote for your favorite canine cancer heroes. Your voting dollars will go to The Broad Institute again this year, and we want to raise as much as we can to further their work. Their research is international and encompasses canine cancer exploration at the DNA level. Last year the calendar contest winners chose to fund Broad’s Canine Osteosarcoma study. This year’s winners will have the same opportunity to choose which study to support.

And the work Broad does is translational*, which means it helps in human cancer research as well.

Some Background — Since the Human Genome Mapping Project began, $3 billion has been spent over 15 years to generate a reliable sequence of the human genome. Sequence of the canine genome was generated in 2004, taking only about a year to finish and costing about $50 million. (Source.)

Throughout this period of intense research, an important fact has emerged. People and dogs are extraordinarily similar in a genetic sense. But while it takes thousands of human patients with cancer to identify risk factors, it only takes maybe 100 canine patients to identify these factors in dogs. This is because their genetic makeup is not as ‘noisy’ as that of humans. As such, researchers can look at the genetics of cancer in dogs to accelerate discoveries that will benefit both dogs and people.

As you probably already know, the statistics on cancer in dogs are alarming, and in fact, the current rate of cancer is higher in dogs than it is in humans.

But did you know that dogs are:

  • Twice as likely to develop leukemia than humans.
  • Four times more likely to suffer from breast cancer.
  • Eight times more likely to develop bone cancer.
  • An incredible thirty-five times more at risk for developing skin cancer. (Source.)

So, besides voting in the calendar contest to support the work of Broad, how can you help further the research they’re doing the rest of the year?

Broad needs DNA samples from purebred dogs who have been diagnosed with the cancers Broad is studying, as well as from older, healthy dogs (ages 8+ years) from the same breeds. Currently those cancers are: Hemangiosarcoma, Osteosarcoma (bone cancer), Lymphoma, Mast Cell Tumors, Mammary Tumors, Melanoma (skin cancer), and Glioma (tumors that start in the brain or spine).

Why are DNA samples important? At its deepest root, cancer is caused by damage to the DNA. DNA is found in every cell and is responsible for directing cells in normal behavior patterns. Under normal circumstances, the body is able to repair DNA damage, but when that damage isn’t repaired, the cells begin to behave abnormally, beginning the out-of-control growth that leads to cancer formation. (Source.)

Why purebred dogs? In developing breeds, certain physical features (size, shape, coat, color) and behaviors were selected by breeders. This genetic diversity makes purebreds dogs ideal for genetic research. Using samples from only purebred dogs ensures the fastest progress for all dogs.

If your purebred dog has had cancer or is an older, healthy dogs (age 8+) please visit www.broadinstitute.org/dogsamples where you’ll find information to guide you on working with your vet to collect and ship blood samples to use in their studies.

To learn more about the breeds they study and the work your votes will be funding, please follow this link: www.broadinstitute.org/dogresearch.

Broad Institute on blackBroad’s Ethical Statement: The Broad Institute’s Canine Disease Mapping group performs disease research under a conservative ethical model that no harm should come to the dogs. Dogs enrolled in their studies are pet dogs, participating after owner consent, only in ways that do not harm them. They DO NOT induce cancer in dogs, nor do they ever keep any animals in the laboratory.

Thank you for supporting the efforts of 2 Million Dogs and The Broad Institute through your participation in the 2014 “Cancer Can’t Keep a Good Dog Down” calendar. Don’t forget to cast your votes for your favorite dogs before voting ends at midnight, EDT, August 8th.

*Translational research is research in the laboratory with an eye toward learning things that could be brought back to patients (both animal and human) in the clinical setting.

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Let The Voting Begin!

Posted by Erich Trapp on July 10, 2013

dancing-dog-cartoonVoting for the 2014 Cancer Can’t Keep a Good Dog Down calendar contestants has begun and runs through midnight, August 8, EDT.

Here’s the link to take you to voting. Either click on it or cut and paste it into your browser.

https://2md2m.ejoinme.org/MyEvents/2014CalendarContest/FundraiserDirectory/tabid/476351/Default.aspx

Just follow the directions on the welcome page and scroll on down to see all the contestants. Clicking on their names will take you to their pages where you can cast your votes.

Votes start at a minimum of $5.00 and increase in whole dollars after that. Every time you log on to vote, you have to start with a $5.00 minimum. (For example. I want to vote for my dog Spot. I log on and spend 5 bucks on Spot. Tomorrow I notice Spot is trailing and I have to bump him up. I still have to start with a $5.00 minimum. Of course, this IS Spot we’re talking about, and he’s worth a lot more than 5 bucks!)

Please check out all the beautiful puppers. Leave no pup behind!

You can vote as often as you like for as many dogs as you like. Bookmark the page so you can keep up with your favorite contestants.

The top 13 dogs with the most votes will be the 2014 calendar dogs. Their people will have the opportunity to vote on which study with the Broad Institute donations will fund.

Remember — all the dogs will appear in the Photo Gallery.

Questions? Problems voting? Email Erich at erich@2milliondogs.org.

Have fun and Puppy Up!

Posted in 2014 Calendar Contest, Fundraiser, Research | Tagged: , , , , , , | 1 Comment »