2 Million Dogs – The Blog

Cancer. Touches. Everyone.

Posts Tagged ‘Canine Lymphoma’

More Ways to Help

Posted by Erich Trapp on July 23, 2013

broad boxerOur “Cancer Can’t Keep a Good Dog Down” 2014 calendar is in full swing, so stop by and vote for your favorite canine cancer heroes. Your voting dollars will go to The Broad Institute again this year, and we want to raise as much as we can to further their work. Their research is international and encompasses canine cancer exploration at the DNA level. Last year the calendar contest winners chose to fund Broad’s Canine Osteosarcoma study. This year’s winners will have the same opportunity to choose which study to support.

And the work Broad does is translational*, which means it helps in human cancer research as well.

Some Background — Since the Human Genome Mapping Project began, $3 billion has been spent over 15 years to generate a reliable sequence of the human genome. Sequence of the canine genome was generated in 2004, taking only about a year to finish and costing about $50 million. (Source.)

Throughout this period of intense research, an important fact has emerged. People and dogs are extraordinarily similar in a genetic sense. But while it takes thousands of human patients with cancer to identify risk factors, it only takes maybe 100 canine patients to identify these factors in dogs. This is because their genetic makeup is not as ‘noisy’ as that of humans. As such, researchers can look at the genetics of cancer in dogs to accelerate discoveries that will benefit both dogs and people.

As you probably already know, the statistics on cancer in dogs are alarming, and in fact, the current rate of cancer is higher in dogs than it is in humans.

But did you know that dogs are:

  • Twice as likely to develop leukemia than humans.
  • Four times more likely to suffer from breast cancer.
  • Eight times more likely to develop bone cancer.
  • An incredible thirty-five times more at risk for developing skin cancer. (Source.)

So, besides voting in the calendar contest to support the work of Broad, how can you help further the research they’re doing the rest of the year?

Broad needs DNA samples from purebred dogs who have been diagnosed with the cancers Broad is studying, as well as from older, healthy dogs (ages 8+ years) from the same breeds. Currently those cancers are: Hemangiosarcoma, Osteosarcoma (bone cancer), Lymphoma, Mast Cell Tumors, Mammary Tumors, Melanoma (skin cancer), and Glioma (tumors that start in the brain or spine).

Why are DNA samples important? At its deepest root, cancer is caused by damage to the DNA. DNA is found in every cell and is responsible for directing cells in normal behavior patterns. Under normal circumstances, the body is able to repair DNA damage, but when that damage isn’t repaired, the cells begin to behave abnormally, beginning the out-of-control growth that leads to cancer formation. (Source.)

Why purebred dogs? In developing breeds, certain physical features (size, shape, coat, color) and behaviors were selected by breeders. This genetic diversity makes purebreds dogs ideal for genetic research. Using samples from only purebred dogs ensures the fastest progress for all dogs.

If your purebred dog has had cancer or is an older, healthy dogs (age 8+) please visit www.broadinstitute.org/dogsamples where you’ll find information to guide you on working with your vet to collect and ship blood samples to use in their studies.

To learn more about the breeds they study and the work your votes will be funding, please follow this link: www.broadinstitute.org/dogresearch.

Broad Institute on blackBroad’s Ethical Statement: The Broad Institute’s Canine Disease Mapping group performs disease research under a conservative ethical model that no harm should come to the dogs. Dogs enrolled in their studies are pet dogs, participating after owner consent, only in ways that do not harm them. They DO NOT induce cancer in dogs, nor do they ever keep any animals in the laboratory.

Thank you for supporting the efforts of 2 Million Dogs and The Broad Institute through your participation in the 2014 “Cancer Can’t Keep a Good Dog Down” calendar. Don’t forget to cast your votes for your favorite dogs before voting ends at midnight, EDT, August 8th.

*Translational research is research in the laboratory with an eye toward learning things that could be brought back to patients (both animal and human) in the clinical setting.

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Congratulations and Thank You!

Posted by Erich Trapp on August 13, 2012

I can’t stop smiling!

2 Million Dogs is pleased to announce the winners of this year’s Cancer Can’t Keep a Good Dog Down calendar contest. They are:

Lily Lisle
Lily Humphrey
Villainous Vida von Wuffenhund Juno
Bailey Sandberg
Rio Monroe
Frasier Metcalf
Harley & Max Waterloo
Charlie Plank
Java Bell
Daisy Powell
Chase Weinand
Max Uphus
Tiny Turcan

We sincerely thank everyone who participated so generously and enthusiastically in this year’s contest, proceeds from which will be given to The Broad Institute. We will be announcing which Broad study the winners pick in a few days, so stay tuned.

Please remember, ALL the dogs (and the kitty) who were entered into the contest will appear in the Gallery. No one gets left behind.

And a very special thanks to the individuals who so kindly voted for the 14 dogs who had no votes.

We hope to have the calendars ready for sale by early October. They will be available through our store on our web site. I’ll post the link when they go on sale.

Thank you, everyone. Puppy Up!

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Less Than An Hour To Go

Posted by Erich Trapp on August 8, 2012

“I’m so excited, I could just …!”

Can you feel the excitement?

We can here at mission control. Less than an hour to go and voting is wild! Remember, voting ends at midnight, Eastern Daylight time.

You can still vote here.

Thank you, everyone. And puppy up!

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Have You Forgotten Us?

Posted by Erich Trapp on August 8, 2012

Of the 91 beautiful faces in this year’s calendar contest, 14 haven’t even 1 single vote. Not even 1.

Update! Some very nice humans have gone in and voted for the dogs who had no votes. From all of them, we say Thank You!

Now EVERYONE has some votes.

They are:

Delilah Massmann

Dylan Lawfer

Fluffy House

Gordon McCarthy

Magic Ianello

Mikey Moran

Nemo Bridges

Nikita Marie Sue Beatty

Norton Forsyth

Oliver Malchow

Sunday DeBow

Tamaiijja Polcyn

Timber Spray

Jeopardy Kennedy Patzman

Thank you, and Puppy Up!

 

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One More Day!

Posted by Erich Trapp on August 8, 2012

“Still time to vote!”

Time’s almost up for this year’s Cancer Can’t Keep a Good Dog Down calendar contest voting.

But you still have until midnight Eastern to vote. (That’s 11 PM Central, 10 PM Mountain, and 9 PM Pacific.) Still plenty of time to vote for your favorite puppers. Please go here to vote.

When will we know who has won? Please give us some turn-around time to check all the numbers. But you can get a pretty good idea by clicking on the link above and keeping track of the totals.  We’ll post winners and all the totals to our blog here, and we’ll send the individual winners email notices.

If you have any burning questions, please email me at erich@2milliondogs.org.

Good luck! And thanks to everyone who participated.

 

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Featured Pup — Alenoush Sullivan

Posted by Erich Trapp on August 4, 2012

Alenoush Sullivan

Meet Alenoush Sullivan, one of our featured pups for the 2 Million Dogs’ 2013 Cancer Can’t Keep a Good Dog Down calendar contest.

(by Gloria Sullivan) Alenoush came to live with us as a foster dog in August of 2010.  This poor old boy had been through some really rough times; he was malnourished, missing teeth, his ears had been cut, he had a chain imbedded in his neck,  was bitten by a snake, and was heartworm positive.

After taking him in, we knew right away that he was special.  Ally was the sweetest, gentlest soul, (his name even means “sweet white wave”); he wanted nothing more than to be next to us, enjoying the love we gave him. Last November, he was diagnosed with soft tissue sarcoma. We opted not to put him through chemo, given his heartworm history and age. We tried oral chemo, but the tumors spread rapidly and on January 4 of this year we lost our “sweet white wave.”  Even though he was not with us for long, he gave so much to us, and we are so grateful that we were able to give him what was probably the best year and a half of his life.

 

Voting continues through August 8th at midnight EDT. For more information, email erich@2milliondogs.org  To vote for these terrific puppers, please click on this link.   It will take you directly to the list of all the contestants. Click on the pup(s) of your choice. To vote, click on “Click here to donate” at the top of their page, just underneath the title.

Don’t miss out on your chance to share the excitement and put your favorite dog on this year’s “Cancer Can’t Keep a Good Dog Down” 2 Million Dogs’ calendar. Voting has been fast and furious, so don’t delay!

Proceeds from this year’s calendar will go to The Broad Institute, doing research in the genomics of canine cancer. Look for more details here.  Our 13 top winners will decide which of three studies we will fund: osteosarcomas, mass cell tumors, or lymphoma.

Every vote is a dollar well-spent, searching for the causes of cancer. We’re working with researchers investigating cancer through comparative oncology, and searching for ways to stop cancers before they start.

Please join us in making a difference — until Cancer. Touches. No one.

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Featured Pup — Abby Knoche

Posted by Erich Trapp on August 4, 2012

Abby Knoche.

Abby Knoche is one of our featured pups for the 2 Million Dogs’ 2013 Cancer Can’t Keep a Good Dog Down calendar contest.

(by Nancy Knoche) We adopted Abby, an 8-year-old female Sheltie, in December 2009. She was our first dog. Her original owners never had her spayed and by May of 2010 she had developed breast cancer, something our vet warned us could happen when he spayed her. We spent the summer traveling 90 minutes to a veterinary oncologist every three weeks. Abby handled the chemo like a trooper and never lost her sweet disposition (or her hair!). After a short respite, the tumors returned in October. A radical mastectomy gave us more time to love her, and again she handled it all with unbelievable ease, greeting the trick-or-treaters at our door with a wagging tail the very day she came home from the vet’s. She even raised money for 2 Million Dogs, proudly wearing her “Puppy Up!” bandana around the neighborhood. We savored our winter months with her, but by April 2011 we knew it was time to let her go. She was such a fighter to the very end. We called her our big hairy bag of love. She will always be the dog of our hearts.

Alan & Nancy Knoche

Voting continues through August 8th at midnight EDT. For more information, email erich@2milliondogs.org  To vote for these terrific puppers, please click on this link.  It will take you directly to the list of all the contestants. Click on the pup(s) of your choice. To vote, click on “Click here to donate” at the top of their page, just underneath the title.

Don’t miss out on your chance to share the excitement and put your favorite dog on this year’s “Cancer Can’t Keep a Good Dog Down” 2 Million Dogs’ calendar. Voting has been fast and furious, so don’t delay!

 
Proceeds from this year’s calendar will go to The Broad Institute, doing research in the genomics of canine cancer. Look for more details here. Our 13 top winners will decide which of three studies we will fund: osteosarcoma, mass cell tumors, or lymphoma.

Every vote is a dollar well-spent, searching for the causes of cancer. We’re working with researchers investigating cancer through comparative oncology, and searching for ways to stop cancers before they start.

Please join us in making a difference — until, together we can say: Cancer. Touches. No one.

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What? Say it isn’t so!

Posted by Erich Trapp on July 31, 2012

What??? Some dogs have NO VOTES? That can’t be right. Are you trying to break my heart??

We have a terrific line-up of beautiful dogs this year, but I noticed there are at least 50 dogs who haven’t been voted for even once. Really? That can’t be right.

So I’m thinking, maybe everyone doesn’t have the right link for voting? So I’m posting it again. You only have until August the 8th at midnight EDT to rally the troops and get friends and family (and you) to vote for your pupper(s). If you have any questions about voting, please email me at erich@2milliondogs.org.

OK, here’s the link to the Fundraiser Directory.  You can keep track of the voting tallies there.

And here’s a fun little video about voting you can send to friends and family: http://www.youtube.com/watch?v=fpFmhezokO0

Remember, votes are only $1.00 (starting at $5.00 and > in dollar increments thereafter). Your votes not only go towards your favorite pup but the money we raise will help fund one of three studies with The Broad Institute. Why is this important? Because, among other things, they are studying the genomics of some major canine cancers: lymphoma, mast cell tumors, and osteosarcoma. In so many of the stories this year, these were three of the predominant cancers. Your voting dollars can contribute to helping find the causes of canine cancer.

The 13 dogs with the most votes not only win a month on the calendar (or the cover), but their people decide which of the three studies above 2 Million Dogs will help fund. You can’t get more direct involvement than that unless you’re the one holding the test tube!! Yes, your votes matter. Not only to these dogs, but to so many other pups stricken with cancer.

2 Million Dogs knows there are many organizations to which you can send your money. We appreciate your involvement with us. And there are many organizations looking to find cures, and that’s admirable too. But why not look at the causes of cancer, so fewer dogs have to suffer to begin with? Help us get to the heart of the matter.

Cancer. Touches. Everyone.

Help us fund the research that has the potential to find a way to stop it before it starts.

Thank you.

In case you’re in the mood for it, here’s a bit of geek for you:

Genetics scrutinizes the functioning and composition of the single gene whereas genomics addresses all genes and their inter relationships in order to identify their combined influence on the growth and development of the organism.

What’s the difference between genetics and genomics?

Genetics is the study of single genes and their effects. For example, Huntington’s or Tay-Sachs disease would be considered “genetics” because a single gene causes these diseases, despite environmental interactions.

Genomics is the study of all your genes including interactions of those genes with each other and with your environment. For example, heart disease, asthma, diabetes, and cancer would all be considered “genomics” because they are caused by genetic and environmental factors.

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Come Vote For Us!

Posted by Erich Trapp on July 28, 2012

“You betcha I’m going to vote. Now where did that cat put Mommy’s credit card?”

You cannot resist me. You must come and vote …

Some really nice (and very tired) man has posted ALL our stories and photos, and now it’s time for you to vote for us. There are a lot of us to look at and admire. We’ll make you laugh and cry, and inspire you with our fortitude and love. So, don’t just sit there. (Yeah, I see you.) Click on the link (after all, you have those fancy opposable thumbs) and start voting.

Sit. Stay. Until you’ve voted … every day.

Your voting dollars not only help choose the winning 13 puppers this year, but your dollars will help support funding research with The Broad Institute. That’s very important. Follow this link to find out why.

 

PS — Thank you. And puppy up!

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Voting is Live!

Posted by Erich Trapp on July 26, 2012

“I can’t wait to vote! Click here to see our cool video.”

Voting for the 2013 Cancer Can’t Keep a Good Dog Down is now Live!

Here’s the link to take you to voting. Instructions are there.

Check out all the terrific contestants we have in this year’s calendar contest and go vote for your favorites! (Yes, that’s plural. Of course!)
Voting has been extended to August 8th, midnight EDT. So you have plenty of time to vote early and often.

Remember, your voting dollars will help decide the 13 winners of this year’s contest and proceeds will go to help fund a study with The Broad Institute.

THANKS to everyone who entered the contest. All your puppers are beautiful! Entries have now closed — but don’t forget to vote! Voting continues through August 8th at midnight EDT.

For more on the calendar, please visit our blog here.

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