2 Million Dogs – The Blog

Cancer. Touches. Everyone.

Archive for December 21st, 2010

Notes on Murphy

Posted by Erich Trapp on December 21, 2010

From 2 Dogs 2000 Miles, Tuesday, December 21, 2010.

Dictating my thoughts for the oncologists at CSU, others who have dogs with nasal adenocarcinoma, and in the interest of science.

Over the weekend Murphy’s ability to breath through his snout has diminished significantly. It seems this new tumor is spreading quickly. We hope the radiation will stop this growth almost immediately. In layman’s terms here’s how it works:

Cancer cells are referred to as ‘immortal’ because they divide unabatedly. The first one, not sure what scientists call it; perhaps the parental or originator, has a gene that for some reason is turned on telling it to start dividing. That one cell becomes two which becomes four, etc. until you have a tumor mass consisting of millions of cells. Radiation therapy attempts to interfere with the tumor cells’ ability to continue mitotic division thereby stopping growth. The cells that can’t divide eventually die off.

Back to Murphy. Even if this massive three day dose of radiation halts tumor growth, it’ll still be restricting airflow in the interim. We’ve already discussed a surgical option in Dr. Withrow’s words taking a roto-router and cleaning the tumor out but that presents some serious problems.

That got me thinking this morning. How can we improve breathing through his snout without surgery and how do we do something like this in humans? Well we know that when people have clogged arteries we place a stent in them permitting improved blood flow. Plus, stents are now drug delivery systems so this might be a way to administer chemo directly into the tumor site.

Must discuss this with Dr. Withrow…

Posted in Uncategorized | Tagged: , , , , , , , | 1 Comment »

Luke Robinson — one of 25 Pet People of 2010.

Posted by Erich Trapp on December 21, 2010

Luke has been selected by Petside.com as one of the top 25 Pet People of 2010, along with Betty White, Bernadette Peters, Kevin Costner, Mimi Ausland (creator of freekibble.com), Ellen DeGeneres, Debi Boies, (co-founder of Pilots N Paws), and others. Congratulations Luke, Hudson, and Murphy, for your untiring work and dedication.

After losing his Great Pyrenees,  Malcolm to bone cancer, Luke Robinson sold his truck, put his stuff in storage and set off on a 2,300 mile walk from Austin, Texas, to Boston, Massachusetts, to raise awareness about the disease that’s killing so many of our pets today.

After more than two years on the road, Robinson, along with his other “boys” (Hudson and Murphy, also Great Pyrenees) completed the arduous trek this summer.

“Walking the final mile from Back Bay Fens to Boston Common was bittersweet,” recalls Robinson. “It marked the end of a long journey, the fulfillment of promise I made to Malcolm but the beginning of a new phase of my life as well.”

Robinson is writing a book about his experience and has started the foundation 2 Million Dogs to raise money for canine cancer research. He is also planning a documentary.

Thank you Maryann Mott for being the advocate for making them in the top 25 pet people of the year.

Posted in Uncategorized | Tagged: , , , , , | 1 Comment »

Current Clinical Trials at the The University of Missouri

Posted by Erich Trapp on December 21, 2010

Cancer Patients Sought for Funded Clinical Trials

The University of Missouri is currently seeking patients for enrollment in funded oncology clinical trials. Study goals and suitability for each patient are discussed in detail with the clients prior to enrollment. Although clinical trial enrollment may not be the best option for all patients, in many cases, clinical trial participation provides the opportunity to receive novel, cutting-edge therapies free of charge or at a reduced cost and may facilitate treatment of pets where it would not otherwise be possible due to financial constraints or lack of other therapy options. Criteria for enrollment are outlined for each tumor type. Please direct referrals or questions to Debbie Tate, RVT (clinical trials coordinator) or the Oncology Clinical Trials Service at 573-882-7821.

For the full article, please follow this link.

There is quite an extensive list of studies on their website. Scroll down their page for more information on:

• Palladia™ for Canine Splenic Hemangiosarcoma
• Inhalant chemotherapy for canine lung cancer (NOT OPEN YET)
• Radioactive Gold Nanoparticles or Palladium Brachytherapy for imaging and treatment of canine prostate cancer
• Tavocept use to mitigate nephrotoxicity associated with cisplatin and piroxicam treatment of canine bladder cancer
• Bcl-2 Canine Lymphoma Study
• AD-198 Canine Refractory Lymphoma Study
• CycloSam™ (Sm-153-DOTMP) OSA Study
• Echocardiographic and Total Body Water Evaluation of Canine Lymphoma

Posted in Uncategorized | Tagged: , , , , , , , , , | Leave a Comment »